Summary: Currently plasma and
blood glucose are used
interchangeably, with risk of
clinical misinterpretation.
Different systems for measuring
glucose concentration may detect and
report fundamentally different
quantities due to differences in the
water content of serum, plasma,
blood and calibrators. It is
recommendation of the IFCC that, for
harmonization of results and
reduction in therapeutic
misjudgments, all glucose results be
reported in terms of glucose in
plasma, regardless of the actual
sample type or measurement
technique. Additionally, there all
multiple sources of error in the
pre-analytical and analytical phases
of POC glucose testing. These will
be reviewed in this presentation.
Objectives:
-
Clarify the relationship between
serum, plasma, and blood glucose
concentrations
-
Assess
the impact of direct vs.
indirect biosensor technology on
the accuracy of glucose
measurements
-
Describe analytical limitations
of the various glucose
measurement methodologies
-
Review
pre-analytical and analytical
causes of error in glucose POCT
measurements
Vendor
Sponsors: Alere; Eurotrol;
Medical Automation Systems,
Radiometer
About
our Speaker:
Dr. Ellis Jacobs is Associate
Professor of Pathology at NYU School
of Medicine, Associate Director of
Clinical Pathology of the South
Manhattan Health Network, Director
of Pathology at Coler-Goldwater
Memorial Hospital and Director of
Chemistry & Point of Care Testing at
Bellevue Hospital Center. Dr.
Jacobs obtained a B.S. degree in
Chemistry and Natural Sciences from
Muhlenberg College in Allentown, PA,
in 1974, and received his Ph.D. in
Biochemistry from the University of
South Carolina in 1979. He
completed postdoctoral training in
Clinical Chemistry & Toxicology at
the University of North Carolina,
Chapel Hill in 1981. He joined the
New York State (NYS) Department of
Health (DOH) as the Director of the
Clinical Laboratory Evaluation
Program in 2002 and in 2005 was
appointed Head of the NYS DOH
Therapeutic Substance Monitoring and
Clinical & Forensic Toxicology
Proficiency Testing Programs, and
Head of the NYS DOH Limited Service
Laboratory Accreditation Program. He
assumed his current positions in
2008.
